J Oldenburg Selected Research

Blood Coagulation Factors (Coagulation Factor)

11/2016	VKCFD2 - from clinical phenotype to molecular mechanism.
6/2015	No increased bleeding risk for oral surgery in patients with severe congenital bleeding disorders due to intense perioperative management.
5/2015	Treatment of minor severe acquired haemophilia. Is there a rationale for immunoadsorption?
5/2014	Novel products for haemostasis - current status.
5/2011	Prevalence of nucleic acid sequences specific for human parvoviruses, hepatitis A and hepatitis E viruses in coagulation factor concentrates.
1/2009	Successful angiographic embolization of recurrent elbow and knee joint bleeds in seven patients with severe haemophilia.
12/2008	[Congenital coagulopathies and coagulation factor inhibitors].
3/2008	Efficient factor VIII affinity purification using a small synthetic ligand.
11/2007	Rehabilitation of synovitis in patients with haemophilia.
7/2007	VKORC1: molecular target of coumarins.

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J Oldenburg Research Topics

Disease

76	Hemophilia A (Haemophilia) 08/2019 - 01/2000
37	Hemorrhage 07/2017 - 04/2000
10	Joint Diseases (Joint Disease) 01/2017 - 09/2006
6	Hemophilia B (Haemophilia B) 11/2017 - 04/2000
6	von Willebrand Diseases (von Willebrand's Disease) 01/2017 - 06/2000
6	Pain (Aches) 01/2017 - 11/2007
6	Neoplasms (Cancer) 01/2016 - 05/2010
4	Infections 01/2017 - 08/2008
4	Testicular Neoplasms (Testicular Cancer) 01/2016 - 04/2009
4	Seminoma 01/2016 - 03/2006
3	Inflammation (Inflammations) 09/2016 - 01/2006
3	Thrombosis (Thrombus) 01/2015 - 05/2010
3	Coumarin Resistance 01/2014 - 01/2011
3	Liver Cirrhosis (Hepatic Cirrhosis) 08/2011 - 04/2010
3	Hypersensitivity (Allergy) 01/2010 - 03/2001
2	Afibrinogenemia (Fibrinogen Deficiency) 11/2016 - 04/2007
2	Type 2 Combined Deficiency Of Vitamin K-Dependent Clotting Factors 11/2016 - 07/2007
2	Autoimmune Diseases (Autoimmune Disease) 09/2015 - 05/2010
2	Genetic Predisposition to Disease (Genetic Predisposition) 12/2014 - 03/2001
2	Hepatitis A (Hepatitis, Infectious) 05/2011 - 05/2002
2	Fibrosis (Cirrhosis) 09/2010 - 04/2010
2	Disease Progression 02/2003 - 02/2003
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2021
1	Type 3 von Willebrand Disease 11/2018
1	Rheumatoid Arthritis 09/2016
1	Osteoarthritis 09/2016
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2016
1	Activated Protein C Resistance (APC Resistance) 01/2016
1	Weight Loss (Weight Reduction) 01/2015

Drug/Important Bio-Agent (IBA)

42	Factor VIII (Coagulation Factor VIII)IBA 08/2019 - 01/2000
16	Blood Coagulation Factors (Coagulation Factor)IBA 11/2016 - 12/2000
13	Proteins (Proteins, Gene)FDA Link 08/2019 - 05/2002
7	AntibodiesIBA 01/2013 - 01/2000
6	Factor IX (Coagulation Factor IX)FDA LinkGeneric 07/2017 - 03/2001
5	A-factor (Streptomyces)IBA 01/2017 - 06/2000
5	Fibrinogen (Factor I)FDA Link 11/2016 - 04/2007
4	Vitamin K FDA Link 11/2016 - 12/2000
4	human F8 protein FDA Link 09/2016 - 01/2013
4	AutoantibodiesIBA 05/2015 - 03/2008
3	von Willebrand FactorIBA 11/2018 - 06/2000
3	Factor XIII (Coagulation Factor XIII)IBA 05/2017 - 09/2007
3	Biomarkers (Surrogate Marker)IBA 09/2016 - 09/2010
3	EpitopesIBA 09/2016 - 03/2002
3	von Willebrand factor drug combination factor VIIIIBA 01/2016 - 05/2012
3	Warfarin (Coumadin)FDA LinkGeneric 01/2014 - 06/2001
2	AntigensIBA 11/2018 - 01/2015
2	nonacog beta pegolIBA 11/2017 - 07/2017
2	recombinant factor VIII N8IBA 09/2016 - 01/2015
2	6-pyruvoyltetrahydropterin synthase (PTPS)IBA 05/2016 - 03/2016
2	Carboplatin (JM8)FDA LinkGeneric 01/2016 - 05/2015
2	Factor X (Stuart Factor)IBA 05/2015 - 05/2009
2	Cisplatin (Platino)FDA LinkGeneric 05/2015 - 04/2009
2	Nonsense Codon (Nonsense Mutation)IBA 05/2014 - 03/2013
2	CoagulantsIBA 01/2014 - 02/2003
2	Vitamin K Epoxide ReductasesIBA 05/2013 - 07/2007
2	Messenger RNA (mRNA)IBA 03/2013 - 02/2005
2	Factor V (Coagulation Factor V)IBA 11/2012 - 09/2009
2	Prothrombin (Factor II)IBA 11/2012 - 04/2000
2	Pharmaceutical PreparationsIBA 05/2010 - 07/2007
2	recombinant FVIIa (rFVIIa)FDA Link 05/2009 - 04/2000
2	CoumarinsIBA 07/2007 - 06/2001
2	IsoantibodiesIBA 12/2006 - 03/2002
2	coumarinIBA 03/2001 - 03/2001
1	Immune Checkpoint InhibitorsIBA 01/2021
1	Tyrosine Kinase InhibitorsIBA 01/2021
1	factor VIII-Fc fusion proteinIBA 01/2018
1	1,2-cyclohexanediamine (dach)IBA 07/2017
1	Tissue Inhibitor of Metalloproteinase-1IBA 09/2016
1	Aggrecans (Aggrecan)IBA 09/2016
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2016
1	Matrix Metalloproteinases (MMPs)IBA 09/2016
1	Collagen Type I (Type I Collagen)IBA 09/2016
1	Cartilage Oligomeric Matrix ProteinIBA 09/2016
1	ChondroitinIBA 09/2016
1	3' Untranslated Regions (3' UTR)IBA 07/2016
1	sugar formulated recombinant FVIIIIBA 05/2016
1	Thrombin FDA Link 01/2016
1	factor V LeidenIBA 01/2016
1	Protein CIBA 01/2016
1	Biological ProductsIBA 09/2015
1	Investigational DrugsIBA 09/2015
1	Hemostatics (Antihemorrhagics)IBA 06/2015
1	Factor VII (Proconvertin)IBA 05/2015

Therapy/Procedure

29	Therapeutics 01/2021 - 04/2000
5	Drug Therapy (Chemotherapy) 05/2015 - 03/2006
4	Knee Replacement Arthroplasty (Total Knee Replacement) 10/2015 - 11/2011
3	Arthrodesis 09/2014 - 10/2009
3	Highly Active Antiretroviral Therapy (HAART) 08/2011 - 04/2010
2	Arthroplasty 01/2017 - 11/2010
2	Radiotherapy 05/2015 - 09/2012
2	Prostheses and Implants (Prosthesis) 09/2014 - 10/2009
2	Synovectomy 01/2014 - 11/2007
2	Injections 05/2009 - 11/2007
2	Intravenous Injections 02/2003 - 05/2002
1	Contraindications 01/2021
1	Immunotherapy 01/2021
1	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2017
1	Oral Surgery (Maxillofacial Surgery) 06/2015
1	Lymph Node Excision (Lymph Node Dissection) 05/2015
1	Adjuvant Chemotherapy 02/2015